AN APPROACH FOR IMPROVEMENT OF THE WATER SOLUBILITY OF NIMESULIDE IN SOLID DISPERSION WITH PEG 4000
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چکیده
منابع مشابه
An Approach for Improvement of the Water Solubility of Nimesulide in Solid Dispersion with Peg
INTRODUCTION Many drugs show bioavailability problems due to their low water solubility, slow dissolution rate, and instability in the gastrointestinal tract. Nimesulide is a non-steroidal anti-inflammatory, analgesic and antipyretic agent, chemically is N-(4 nitro-2-phenoxyphenyl) methane sulfonamide. It is poorly soluble in water and irregularly absorbed by gastrointestinal tract. Among the v...
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ژورنال
عنوان ژورنال: IOSR Journal of Pharmacy (IOSRPHR)
سال: 2012
ISSN: 2319-4219,2250-3013
DOI: 10.9790/3013-0220153154